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Tic Disorders


Research articles:

Robertson, M. (2006). Mood disorders and Gilles de la Tourette's syndrome: an update on prevalence, etiology, comorbidity, clinical associations, and implications. Journal of Psychosomatic Research, 61(3), 349-358. doi:10.1016/j.jpsychores.2006.07.019

Abstract: Gilles de la Tourette''s syndrome (GTS) consists of multiple motor tics and one or more phonic tics. Psychopathology occurs in approximately 90% of GTS patients, with attention-deficit/hyperactivity disorder (ADHD) and obsessive–compulsive disorder (OCD) being common. Depression is common, with a lifetime risk of 10% and a prevalence of between 1.8% and 8.9%. Depression and depressive symptoms are found to occur in 13% and 76% of GTS patients attending specialist clinics, respectively. In controlled studies embracing over 700 GTS patients, the patients were significantly more depressed than controls in all but one instance. In community and epidemiological studies, depression in GTS individuals was evident in two of five investigations. Clinical correlates of depression in people with GTS appear to be: tic severity and duration, the presence of echophenomena and coprophenomena, premonitory sensations, sleep disturbances, obsessive–compulsive behaviors/OCD, self-injurious behaviors, aggression, conduct disorder (CD) in childhood, and, possibly, ADHD. Depression in people with GTS has been shown to result in a lower quality of life, potentially leading to hospitalization and suicide. The etiology of depression appears to be multifactorial. Bipolar affective disorder (BAD) and GTS may be related in some individuals. However, it is noted that sample sizes in most of these studies were small, and it is unclear at the present time as to why BAD may be overrepresented among GTS patients. [Copyright &y& Elsevier]


Robertson, M. M., Eapen, V., & van de Wetering, B. M. (1995). Suicide in Gilles de la Tourette's syndrome: Report of two cases. Journal of Clinical Psychiatry, 56(8), Retrieved from EBSCOhost.

Presents 2 cases illustrating the relationship between Gilles de la Tourette's syndrome (TS), suicide, depression, and obsessive-compulsive and self injurious behaviors. A 33-yr-old man and a 27-yr-old woman with TS presented with motor and vocal tics, obsessive-compulsiveness, and self-injurious behavior. Histories of both Ss revealed the presence of multiple stresses, including social stigma, restrictions on autonomy, illness or treatment disrupted normal functioning, limited opportunities for social activities, and burdened families. Despite therapy, both patients committed suicide. It is suggested that TS is a spectrum disorder, with comorbid depression, obsessive-compulsive disorder, attention-deficit disorder, and self injurious behavior. Regular monitoring of mental state, and thorough evaluation of psychosocial and adaptational difficulties coupled with prompt and appropriate intervention in TS cases is essential. (PsycINFO Database Record (c) 2010 APA, all rights reserved)


10/22/2014 at 10:38 PM
Teresa Manley
my son had tourettes. i am trying to understand why he would slitnhis throat at only 26 yrs old. he had a bachelor degree in pre med and traveled to several Asian countries. he immersed into martial arts and Asian cultural ways as a way of self control. he appeared to be optimistic in many difficult times and shared optimism with others no one who knows him can believe h would kill himself. he was against suicide. i just don't know if he did it or was murdered. the examiner in Portland Oregon says suicide. he had a girlfriend who just moved here from Japan to live with him and go to college finish his degree. he was surrounded by strangers and away from all family and friends for only ten days when this happened.
02/25/2013 at 3:37 AM
Gill Jewell
A 32 year old suicide had an auditory tic. This increased around the time of his suicide. Is it an anxiety response/and or a warning sign ? All of the above article pertains to his case eg discriptive data of ur man and woman etc
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